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Endocrine Abstracts

Published by BioScientifica

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ea0090p401 | Pituitary and Neuroendocrinology | ECE2023

Mortality in acromegaly diagnosed in the elderly in Spain is higher in women compared to the general Spanish population

Biagetti Betina , Iglesias Pedro , Villar Taibo Rocio , Dolores Moure Maria , Paja Fano Miguel , Araujo Castro Marta , Ares Blanco Jessica , Cristina Alvarez Escola Maria , Vicente Almudena , Alvarez Guivernau Elia , Novoa-Testa Iria , Cordido Carballido Fernando , Camara-Gomez Rosa , Lecumberri Beatriz , Garcia Gomez Carlos , Bernabeu Ignacio , Manjon Miguelez Laura , Gaztambide Sonia , Webb Susan , Luis Menendez Torre Edelmiro , Jose Diez Juan , Simo Canonge Rafael , Puig-Domingo Manel

Context: There is no data on mortality of acromegaly diagnosed in the elderly. Objective: To compare clinical characteristics, GH-related comorbidities, therapeutic approaches and mortality of patients diagnosed before or after 2010 and to assess overall mortality compared with the general Spanish population. Setting: Spanish tertiary care centers.Design, Patients, and Methods: Retrospective evaluation of 118...
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ea0099p319 | Pituitary and Neuroendocrinology | ECE2024

Natural history of rathke’s cleft cysts. a retrospective analysis of a fifteen centers experience in spain

Luis Menendez Torre Edelmiro , Gutierrez Hurtado Alba , Irigaray Ana , Martin Rojas Patricia , Gonzalez Molero Inmaculada , Vicente Almudena , Araujo Marta , Idobro Cindy , Villar Taibo Rocio , Biagetti Betina , Soto-Moreno Alfonso , Mateu Salat Manel , Guerrero Fernando , Dolores Moure Rodriguez Maria , Paja Fano Miguel , Cordido Fernando , Iglesias Pedro , Dolores Ollero M , Aulinas Maso Ana

Objective: To evaluate the natural history of Rathke’s cleft cysts (RCC).Materials and Methods: A multicenter retrospective clinical practice study of adult patients with radiologically diagnosed RCCs since 2000 in 15 tertiary hospitals (SPAIN-QBR study) with a diameter greater than 5 mm, in whom non-surgical follow-up was decided.Results: A total of 177 patients were followed for 65.8 ± 42.3 months. The mean age was 42.8...
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ea0099p512 | Pituitary and Neuroendocrinology | ECE2024

Transsphenoidal surgical treatment of symptomatic rathke’s cysts. results, follow-up, and recurrence rates

Luis Menendez Torre Edelmiro , Gutierrez Hurtado Alba , Dolores Ollero M , Martin Rojas Patricia , Gonzalez-Molero Inmaculada , Araujo Castro Marta , Idobro Cindy , Dolores Moure Rodriguez Maria , Biagetti Betina , Iglesias Pedro , Paja Fano Miguel , Villar Taibo Rocio , Pena Dubra Alberto , Vicente Almudena , Guerrero Fernando , Cordido Fernando , Aulinas Maso Ana , Mateu Salat Manel , Soto-Moreno Alfonso

Aim: To evaluate the efficacy of transsphenoidal surgery in patients with Rathke cleft cysts (RCCs), and recurrence rates after follow-upMethods: A multicenter retrospective clinical practice study in patients with RCCs operated through transsphenoidal route and followed in 15 tertiary hospitals (SPAIN-QBR study) during 64.0 ± 49.0 months.Results: A total of 85 patients with a diagnosis of RCCs underwent transsphenoidal surger...
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ea0099p524 | Pituitary and Neuroendocrinology | ECE2024

Differences in the efficacy of second-line therapies on the biochemical control of acromegaly in patients with GH secreting pituitary neuroendocrine tumors (Pit-NETs) and GH and PRL cosecreting Pit-NETs

Araujo Castro Marta , Vicente Almudena , Cordido Fernando , Luis Menendez Torre Edelmiro , Pascual-Corrales Eider , Venegas Moreno Eva , Garcia Centeno Rogelio , Villar Taibo Rocio , Guerrero Fernando , Abellan Galiana Pablo , A Hanzu Felicia , Fajardo-Montanana Carmen , Novo Cristina , Camara Rosa , Dolores Aviles Perez Maria , Marazuela Monica , Biagetti Betina , Puig-Domingo Manel

Aim: To evaluate the efficacy of second-line therapies in patients with acromegaly caused by a GH and PRL cosecreting pituitary neuroendocrine tumor (GH&PRL-Pit-NET) and those caused by a GH-Pit-NET.Methods: A multicenter retrospective clinical practice study of 679 patients with acromegaly in follow-up in 33 tertiary hospitals (ACRO-SPAIN study). For this analysis, only patients on treatment with pasireotide or pegvisomant in monotherapy or in combi...
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ea0090p411 | Pituitary and Neuroendocrinology | ECE2023

Usefulness of the short version of the acute octreotide test for prediction of first-generation somatostatin receptor ligands response in acromegaly: a validation study with the ACROFAST cohort

Marques-Pamies Montserrat , Gil Joan , Jorda Mireia , Valassi Elena , Biagetti Betina , Hernandez Marta , Gimenez-Palop Olga , Martinez Silvia , Carrato Cristina , Villar Taibo Rocio , Araujo-Castro Marta , Blanco Concepcion , Simon Inmaculada , Simo-Servat Andreu , Xifra Villarroya Gemma , Vazquez San Miguel Federico , Pavon Isabel , Garcia Centeno Rogelio , Zavala Roxana , Alexandra Hanzu Felicia , Mora Mireia , Aulinas Maso Ana , Vilarrasa N , Soledad Librizzi Maria , Paz De Miguel Novoa Maria , Alvarez-Escola Cristina , Pico-Alfonso Antonio , Antonio Sampedro-Nunez Miguel , Salinas Vert Isabel , Fajardo-Montanana Carmen , Camara-Gomez Rosa , Bernabeu Ignacio , Webb Susan , Marazuela Monica , Puig-Domingo Manel

We previously described a short version of the acute octreotide test (sAOT) for predicting somatostatin receptor ligands (SRLs) response in patients with acromegaly1. In the present work, we prospectively reassess the sAOT ability to identify SRLs response in patients from the ACROFAST study using the current GH standards and control criteria and we also correlate sAOT values with E-cadherin tumor expression. Methods: Patients from the ACROFAS...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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